Штыров Юрий Юрьевич
Институт когнитивных нейронаук
Профессиональные интересы
Должности
- Директор центра — Институт когнитивных нейронаук, Центр исследований интеллекта и когнитивного благополучия
- Ведущий научный сотрудник — Институт когнитивных нейронаук, Центр исследований интеллекта и когнитивного благополучия
- Ведущий научный сотрудник — Институт когнитивных нейронаук, Центр нейроэкономики и когнитивных исследований
Био
- · Начал работать в НИУ ВШЭ в 2013 году.
- · Научно-педагогический стаж: 25 лет.
Образование
- 2001 · PhD: Университет Хельсинки
- 1994 · Специалитет: Санкт-Петербургский государственный университет, специальность «Физиология», квалификация «Биолог-физиолог»
Опыт работы
- · Yury Shtyrov (Professor, Head of MEG/EEG at the Center of Functionally Integrative Neuroscience, Aarhus University; Visiting Professor/PI at the HSE CDM Centre) has many years of international experience in studying human neurocognitive functions, in particular neurobiological foundations of the human speech and language function. His particular contribution to the science of language has been in uncovering early and automatic stages of language processing and in detailing the time course of spoken language comprehension in the brain. This work has to a large extent contributed to a dramatic change in our understanding of how the brain analyses speech, which has occurred in recent years. It shows how memory traces for linguistic elements in the brain can be probed using objective imaging tools, how they develop with learning, interact on different levels, as well as the interaction between the cognitive systems of language and attention. Most importantly, this work shows that these different processes occur rapidly and in parallel, something that was first met with disbelief but is now becoming generally accepted thanks to this and similar work. We are very pleased to have Prof. Shtyrov as our close collaborator in a range of projects focussed on human mechanisms of comminication, perception and cognitive control using MEG, EEG, TMS, behavioural and other methodologies.
- · 2013–настоящее время Professor - Head of MEG Group MINDLab - Centre for Functionally Integrative Neuroscience (CFIN) Institute for Clinical Medicine Aarhus University, Denmark
- · 2011–2012: Professor - Director of the Cognitive Brain Research Unit at the IBS - Universityof Helsinki, Institute of Behavioural Sciences (IBS), Helsinki, Finland
- · 2007–2013: Senior Scientist (Programme Leader Track) and Head of Magneto- and Electroencephalography (since 2011) - Medical Research Council (MRC), Cognition and Brain Sciences Unit. Cambridge, United Kingdom
- · 2000–2007: Research Associate (Post-Doctoral Research Scientist)
- · 2000-2003: / Senior Investigator Scientist
- · 2003-2007: Since
- · 2006: also MEG Lab Manager - MRC Cognition and Brain Sciences Unit. Cambridge, United Kingdom
- · 1997–2000: Researcher - Cognitive Brain Research Unit, University of Helsinki, Helsinki,Finland
- · 1994–1997: Младший научный сотрудник - Отдел физиологии и патологии речи, СПб НИИ Уха, Горла, Носа и Речи. Санкт-Петербург, Россия
Награды и поощрения
- · Благодарственное письмо ректора НИУ ВШЭ (сентябрь 2021)
- · Надбавка за публикацию в журнале из Списка А (и приравненном к нему научном издании) (2025–2026)
- · Надбавка за публикацию в международном рецензируемом научном издании (2021–2022)
Гранты и проекты
- 2015 · AUFF Research Foundation, Denmark, 2014. PI on a 6-month visiting professorship grant, DKK 284 000, 2014-2015.
- 2017 · Lundbeck Foundation, Denmark, 2014. PI on 3-year project grant: Neural Speech Processing as Covert Index of Consciousness in Coma, Vegetative State, and Minimally Conscious Patients. DKK ~1.6 mln (~€ 210 000), 2014-2017.
- 2016 · Lundbeck Foundation, Denmark, 2013. PI on 3-year project grant: Rapid formation of lexical memory circuits in human neocortex. DKK 3 mln (~€ 400 000), 2014-2016.
- — · Pufendorf Institute, Lund, Sweden, 2013. HuMeNs - – Advanced Study Group on neuroscience of knowledge acquisition. Co-applicants: Profs. M. Lindgren, M. Horne, F. Ståhlberg, D Topgaard et al. (Lund U), ~100000 SEK.
- 2017 · Engineering and Physical Sciences Research Council & Medical Research Council, UK, 2012. Co-PI on 5-year partnership programme grant: Building capacity in UK clinical MEG research. Co-applicants: Profs K. Singh (U Cardiff), K. Nobre (U Oxford), Dr G. Barnes (UCL) et al. ~£1.3 mln. 2013-2017.
- 2013 · European Commission Tempus IV programme, 2010. Co-PI on a 3.5-year project grant: Postgraduate training network in biotechnology of 3.5-year project grant. Co-applicants: K. Kaila, (Helsinki U)., I. Pavlov (UCL), A. Shestakova (St. Petersburg U.), V. Klucharev (FC Donders) et al. ~€ 1 mln. 2010-2013.
- 2011 · Federal Agency for Science and Innovation, Russian Federation, 2010. PI on a 2-year project grant №02.740.11.5148: Introduction of novel methodologies into science, medicine and education in RF: using magnetoencephalography for mapping brain function. RUB 2 mln. 2010-2011.
- 2014 · Medical Research Council, UK, 2009. PI on 5-year research programme U.1055.04.014.00001.01: Early automaticity of neural language processing: lexical, morphosyntactic and methodological perspectives. ~£1.4 mln. 2009-2014.
- 2011 · GlaxoSmithKline, UK, 2009. Co-PI on a 2-year industrial collaborative research programme: Biomarkers of schizophrenia. PIs: Profs F. Pulvermuller & Y. Shtyrov. £ 150 000, 2009-2011.
- 2016 · Elekta Neuromag Ltd, Sweden-Finland, 2006. Co-PI on a 10-year industrial research collaboration programme: Clinical utility of magnetoencephalography. PIs: Profs F. Pulvermuller, Y. Shtyrov, R. Henson. £ 100 000. 2007-2016.
- 2009 · European Commission Tempus programme, 2005. Co-PI on a 3.5-year project grant. Co-applicants: Drs I. Pavlov (UCL), A. Shestakova (Helsinki U.), O. Pongs (Hamburg U.), V. Klucharev (FC Donders), I. Kanunikov (St. Petersburg U.). € 500 000. 2006-2009.
- 2003 · Finnish Graduate School of Psychology, 1999. Four-year PhD research fellowship, FIM 400 000. 1999-2003.
- 2000 · Cognitive Brain Research Unit, University of Helsinki, Finland, 1998. Two-year research grant, funded by the Finnish Work Environment Fund. Co-applicant: Dr. T. Kujala. FIM 300 000. 1998-2000
- 1999 · University of Helsinki, Finland, 1998. Six-month personal grant. FIM 9 000. 1998-1999
- — · Centre for International Mobility, Finland, 1998. Six-month personal research grant. FIM 36 000
- 1998 · Centre for International Mobility, Finland, 1997. One-year personal research grant. FIM 60 000. 1997-1998.
Конференции (5)
Показать все
- · 2025: CogSci2025 (Сан-Франциско). Доклад: Age-related changes in cognitive flexibility: fMRI meta‐analysis
- · 2018: 24th AMLaP conference, Architectures and Mechanisms of Language Processing (Берлин). Доклад: PERCEPTUAL PRIMING AND SYNTACTIC CHOICE IN ENGLISH LANGUAGE: MULTIMODAL STUDY.
- · 2018: 24th AMLaP conference, Architectures and Mechanisms of Language Processing (Берлин). Доклад: PERCEPTUAL PRIMING AND SYNTACTIC CHOICE IN RUSSIAN LANGUAGE: MULTIMODAL STUDY.
- · 2017: 5th Polish Eye Tracking Conference (Люблин). Доклад: The role of attention in sentence production: beyond visual modality
- · 2016: 8th Annual Meeting of the Society for the Neurobiology of Language (Лондон). Доклад: The effects of cross-linguistic phonologic and semantic overlap in masked priming paradigm: behavioral and ERP evidence
Идентификаторы исследователя
- ORCID:
0000-0001-7203-4902 - ResearcherID:
I-3421-2013 - Google Scholar: https://scholar.google.ru/citations?user=VqgPbV0AAAAJ&hl=en
- Scopus AuthorID:
6701617874
Публикации (155)
Repetitive transcranial magnetic stimulation modulates action naming over the left but not right inferior frontal gyrus
2022 · ARTICLE · en
fMRI language mapping studies report right-hemispheric contribution to language in healthy individuals. However, it remains unclear whether these right-hemispheric patterns of activity are critical for language, which is highly relevant for clinical preoperative language mapping. The available findings are controversial. In this study, we first measured individual patterns of language lateralization with an fMRI language localizer in healthy participants with different handedness (N = 31). Then, the same participants received rTMS over the individual coordinates of peak fMRI-based activation in the left and right inferior frontal gyri. During rTMS, participants performed a picture naming task. It included both objects and actions to test whether naming of nouns and verbs would be equally modulated by rTMS. Stimulation of the left inferior frontal gyrus resulted in accuracy facilitation of verb production regardless of individual language lateralization. No modulation of object naming was found at any stimulation site in terms of accuracy nor reaction time. This study causally confirmed the critical contribution of the left, but not the right hemisphere to verb production regardless of the language lateralization patterns observed with fMRI. Also, the results stress that action rather than object naming is the task of choice for mapping language in the frontal lobe. © 2022, The Author(s), under exclusive licence to Springer-Verlag GmbH Germany, part of Springer Nature.
Inflectional zero morphology – Linguistic myth or neurocognitive reality?
2022 · ARTICLE · en
Knowledge of language, its structure and grammar are an essential part of our education and daily activities. Despite the importance of language in our lives, linguistic theories that explain how the language system operates are often disconnected from our knowledge of the brain’s neurocognitive mechanisms underpinning the linguistic function. This is reflected, for example, in the inclusion of abstract and often controversial elements into theories of language. Here, we discuss the case of the so-called null constituent and its smallest and the most controversial variant – the zero morpheme, a hypothetical morphosyntactic device that has no overt physical (phonological or orthographic) expression. Focusing on the putative inflectional zero morpheme, we discuss the theoretical origins and pitfalls of this approach and advocate the important role for neurobiological research that could try to elucidate the neurocognitive reality of such constructs in linguistic communication.
Native language experience shapes pre-attentive foreign tone processing and guides rapid memory trace build-up: An ERP study
2022 · ARTICLE · en
Language experience, particularly from our native language (L1), shapes our perception of other languages around us. The present study examined how L1 experience moulds the initial processing of foreign (L2) tone during acquisition. In particular, we investigated whether learners were able to rapidly forge new neural memory traces for novel tonal words, which was tracked by recording learners’ ERP responses during two word acquisition sessions. We manipulated the degree of L1–L2 familiarity by comparing learners with a nontonal L1 (German) and a tonal L1 (Swedish) and by using tones that were similar (fall) or dissimilar (high, low, rise) to those occurring in Swedish. Our results indicate that a rapid, pre-attentive memory trace build-up for tone manifests in an early ERP component at ~50 ms but only at particularly high levels of L1–L2 similarity. Specifically, early processing was facilitated for an L2 tone that had a familiar pitch shape (fall) and word-level function (inflection). This underlines the importance of these L1 properties for the early processing of L2 tone. In comparison, a later anterior negativity related to the processing of the tones’ grammatical content was unaffected by native language experience but was instead influenced by lexicality, pitch prominence, entrenchment, and successful learning. Behaviorally, learning effects emerged for all learners and tone types, regardless of L1–L2 familiarity or pitch prominence. Together, the findings suggest that while L1-based facilitation effects occur, they mainly affect early processing stages and do not necessarily result in more successful L2 acquisition at behavioral level.
Oscillatory beta/alpha band modulations: a potential biomarker of functional language and motor recovery in chronic stroke?
2022 · ARTICLE · en
Stroke remains one of the leading causes of various disabilities, including debilitating motor and language impairments. Though various treatments exist, post-stroke impairments frequently become chronic, dramatically reducing daily life quality, and requiring specific rehabilitation. A critical goal of chronic stroke rehabilitation is to induce, usually through behavioral training, experience-dependent plasticity processes in order to promote functional recovery. However, the efficiency of such interventions is typically modest, and very little is known regarding the neural dynamics underpinning recovery processes and possible biomarkers of their efficiency. Some studies have emphasized specific alterations of excitatory–inhibitory balance within distributed neural networks as an important recovery correlate. Neural processes sensitive to these alterations, such as task-dependent oscillatory activity in beta as well as alpha bands, may be candidate biomarkers of chronic stroke functional recovery. In this review, we discuss the results of studies on motor and language recovery with a focus on oscillatory processes centered around the beta band and their modulations during functional recovery in chronic stroke. The discussion is based on a framework where task-dependent modulations of beta and alpha oscillatory activity, generated by the deep cortical excitatory–inhibitory microcircuits, serve as a neural mechanism of domain-general top-down control processes. We discuss the findings, their limitations, and possible directions for future research.
Electrophysiological Evidence of Dissociation Between Explicit Encoding and Fast Mapping of Novel Spoken Words
2021 · ARTICLE · en
Existing behavioral, neuropsychological and functional neuroimaging data suggest that at least two major cognitive strategies are used for new word learning: fast mapping (FM) via context-dependent inference and explicit encoding (EE) via direct instruction. However, these distinctions remain debated at both behavioral and neurophysiological levels, not least due to confounds related to diverging experimental settings. Furthermore, the neural dynamics underpinning these two putative processes remain poorly understood. To tackle this, we designed a paradigm presenting 20 new spoken words in association with pictures in either FM or EE settings, closely matched for auditory and visual features and overall task demands. We tested word acquisition using a range of behavioral measures as well as passive event-related potential (ERP) responses, an established measure of word memory trace activation, and compared brain activity elicited by novel FM and EE words before and after the learning session. Behavioral data obtained in free recall, recognition and semantic word-picture matching tasks indicated successful acquisition of new words after just 10 exposures. Crucially, we found no behavioral evidence of different acquisition outcomes between FM and EE learning. ERP data, which exhibited the main response peaks at ~170, 250, and 520 ms, also indicated successful learning, with statistically different responses between novel and familiar words present only before, but not after the training, suggesting rapid formation of new neural memory circuits matching in activation those for previously known words. Furthermore, already at the earliest peak, we found different topographic distributions for the two learning types, with left-lateralized FM dynamics, suggestive of core language system involvement, and more diffuse activity for EE items, possibly suggesting the role of attention/executive control network. A similar effect also manifested later, at ~520 ms. Our data suggest that while both EE and FM learning can be successful for rapid word acquisition at the behavioral level, the diverging electrophysiological patterns suggest a dissociation between the neural systems underpinning these learning strategies.
Modulating Novel Vocabulary Acquisition by Transcranial Direct Current Stimulation
2021 · ARTICLE · en
Effects of transcranial direct current stimulation (tDCS) on acquisition of novel vocabulary remain controversial, which could be related to specific neural mechanisms underpinning different language learning strategies. To comprehensively assess tDCS effects on fast mapping (FM) and explicit encoding (EE) of novel words, we modulated tDCS stimulation regime (anodal/cathodal/sham), stimulated hemisphere (left/right), site (Broca/Wernicke/their right-hemispheric homologues), learning type (FM/EE), and active rehearsal (with/without articulation of novel words). Nine groups (n=32 each) of native Russian speakers (age 18–35) received 15 minutes of 1.5mA tDCS before learning eight novel words, presented ten times each in a naturalistic audio-visual word-picture association session. Error rates and reaction times (RTs) were tested immediately after the learning session using recognition and semantic word-picture matching tasks. Learning outcomes were analysed using chi-square (X2) and general linear mixed model (GLMM). Compared with sham (placebo) condition, participants were faster after real tDCS (all p-values
Differential Neural Timecourse of Fast Mapping and Explicit Encoding of Novel Words: EEG and Behavioural Data
2021 · ARTICLE · en
At least two cognitive strategies are used for new word learning: fast mapping (FM) via context-dependent inference and explicit encoding (EE) via direct instruction. However, these distinctions remain debated and the neural dynamics underpinning these processes are poorly understood. To tackle this, we designed a paradigm presenting 20 new spoken words in association with pictures in either FM or EE settings, closely matched for physical features and overall task demands, and tested FM and EE word acquisition in two studies using behavioural measures and passive ERP responses, an established measure of word memory-trace activation. Behavioural data obtained in free recall, recognition and semantic word-picture matching tasks indicated successful acquisition of new words after just 10 exposures in both experiments. For ERP analysis, Study 1 compared brain activity elicited in adult learners (N=12) by novel FM and EE words before and after the learning session. The main ERP peaks at ~170, 250 and 520 ms indicated successful learning, with statistically different responses between novel and familiar words present only before but not after the training, suggesting rapid formation of new neural memory circuits matching in activation those for previously known words. Already at the earliest peak we found different topographic distributions for the two learning types, with left-lateralised FM dynamics, suggestive of core language system involvement, and more diffuse activity for EE items, possibly suggesting the role of attention/executive control network. To explore relationship between behavioural and neural indices and further scrutinise brain bases of these phenomena, we ran Study 2 (N=36). ERPs indicated the most prominent peaks for novel words at ~196 and ~280 ms. We explored pre- vs. post-learning difference responses at these peaks using multiple linear regression and found significant associations between the accuracy in the semantic wordpicture matching task and ERP dynamics. Namely, the use of implicit learning strategy was accompanied by a positive-going ERP amplitude change at the first peak (p=0.015). For EE items, however, linear regression revealed a significant contribution by a negative-going dynamics at the second peak (pb0.043). Source reconstruction (sLORETA) indicated anterior-temporal lobes of both hemispheres as the main generators of these dynamics, with left ATL being predominantly activated for FM, and bilateral activity for EE. In sum, while both learning strategies can be successful for rapid word acquisition, diverging electrophysiological patterns suggest a spatiotemporal dissociation between neural systems underpinning these learning strategies. Supported by the grant of the Government of RF №14. W03.31.0010 doi:10.1016/j.ijpsycho.2021.07.276
Eye tracking methods in psycholinguistics
2021 · CHAPTER · en
Rapid technological advancements have led to a significant progress in research methods for cognitive sciences. Today scientists can easily use various neurophysiological methods in order to study human behavior and its underlying brain mechanisms and cognitive processes. Among such methods is eye-tracking — a technique allowing recording and analysis of the online oculomotor behavior. Since the end of the 19th / beginning of the 20th century (Javal, 1879; Huey, 1908), recording and analysing eye movements became an important and effective tool in cognitive research. In this chapter, we first review the use of eye-tracking methodology for cognitive research, both as a stand-alone method and in combination with electroencephalography. We then discuss eye-tracking in terms of its use in language research, from studying sentence comprehension and sentence production, to second language learning and bilingualism. Finally, we will talk about co-registration of brain-ocular activity.
Individual differences in bilingual experience modulate executive control network and performance: Behavioral and structural neuroimaging evidence
2021 · ARTICLE · en
Dual / multiple language use has been shown to affect cognition and its neural substrate, although the replicability of such findings varies, partially due to neglecting the role of interindividual variability in bilingual experience. To address this, we operationalized the main bilingual experience factors as continuous variables, investigating their effects on executive control performance and neural substrate deploying a Flanker task and structural magnetic resonance imaging. First, higher L2 proficiency predicted better executive performance. Second, neuroimaging results indicated that bilingualism-related neuroplasticity may peak at a certain stage of bilingual experience and eventually revert, possibly following functional specialization. Importantly, experienced bilinguals optimized behavioral performance independently of volumetric variations, suggesting a degree of performance gain even with lower GMV. Hence, the effects of bilingualism on cognition may evolve with experience, with improvements in functional efficiency eventually replacing structural changes. We conclude that individual differences in bilingual experience modulate cognitive and neural consequences of bilingualism.
Bilingualism and Reserve: Etiology of Successful Aging
2021 · CHAPTER · en
In bilingualism research, there is a rapidly growing interest towards potential neuroprotective mechanisms against age-related cognitive decline, supported by dual and multiple language use. In this brief review, we discuss existing evidence, which generally suggests that bilingualism may foster neuroplastic changes resulting in beneficial consequences for the brain both at the structural level and at the functional one during later stages of life. First, we outline the interplay between the neural function and the bilingual experience. We then propose how bilingual and multilingual experience may protect the mind and the brain from the age-related cognitive decline and its consequences. We continue by discussing the notions of cognitive and brain reserve and contextualize existing findings from bilingualism literature with regard to this newly proposed reserve framework. We highlight how bilingualism-induced neural and cognitive changes may pave the way for the development of the neural foundations of reserve: both at the neuroanatomical and at the cognitive levels. We conclude our review by proposing possible models of bilingualism-induced successful aging.
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