Печенкова Екатерина Васильевна
Факультет социальных наук
Профессиональные интересы
Должности
- Доцент — Факультет социальных наук, Департамент психологии
- Заведующий лабораторией — Факультет социальных наук, Департамент психологии, Научно-учебная лаборатория когнитивных исследований
Био
- · Начала работать в НИУ ВШЭ в 2018 году.
- · Научно-педагогический стаж: 23 года.
Образование
- 2009 · Кандидат психологических наук: специальность 19.00.01 «Общая психология, психология личности, история психологии», тема диссертации: Виды и механизмы временных смещений в восприятии порядка событий
- 2001 · Специалитет: Московский государственный университет им. М.В. Ломоносова, специальность «Психология», квалификация «Психолог. Преподаватель психологии»
Опыт работы
- · 2013: C исследования в области социальной нейронауки в сотрудничестве с «НИИ нейропсихологии письма и речи»; с
- · 2015 г.: ведущий специалист в «НИИ нейропсихологии письма и речи»
- · 2009–2018: научный руководитель группы функциональной МРТ головного мозга человека Центра лучевой диагностики при Лечебно-реабилитационном центре Минздрава России
- · 2008–2012: преподавание в Российском государственном гуманитарном университете
- · 2007–2008: стажировка в лаборатории М. Поттер, факультет когнитивных наук и наук о мозге, Массачусетский технологический институт (в рамках программы международного обмена Фулбрайта)
- · 2004–2015: зав. кафедрой академической психологии Института практической психологии и психоанализа
- · 2002–2003: преподавание в Московском институте медико-социальной реабилитологии (факультет клинической психологии)
- · 2001–2009: экспериментальные исследования восприятия и внимания человека в проблемной лаборатории «Восприятие» факультета психологии МГУ
- · 2001–2007: преподавание в МГУ им. М.В. Ломоносова (кафедра общей психологии факультета психологии, отделение теоретической и прикладной лингвистики)
Награды и поощрения
- · Надбавка за публикацию в журнале из Списка А (и приравненном к нему научном издании) (2023–2024)
- · Надбавка за публикацию в международном рецензируемом научном издании (2022–2023, 2021–2022, 2020–2022)
- · Надбавка за регулярные публикации в международных рецензируемых научных изданиях (2024–2029)
- · Лучший преподаватель — 2024
Гранты и проекты
- — · на соискание учёной степени кандидата наук
Идентификаторы исследователя
- ORCID:
0000-0003-3409-3703 - ResearcherID:
U-5794-2018 - SPIN РИНЦ:
7226-9591 - Google Scholar: https://scholar.google.com/citations?user=E1BdTUEAAAAJ&hl=en
Публикации (56)
Sensory integration in interoception: Interplay between top-down and bottom-up processing
2021 · ARTICLE · en
Although the neural systems supporting interoception have been outlined in general, the exact processes underlying the integration of visceral signals still await research. Based on the predictive coding concept, we aimed to reveal the neural networks responsible for the bottom-up (stimulus-dependent) and top-down (model-dependent) processing of interoceptive information. In a study of 30 female participants, we utilized two classical body perception experiments—the rubber hand illusion and a heartbeat detection task (cardioception), with the latter being implemented in fMRI settings. We interpreted a stronger rubber hand illusion, as measured by higher proprioceptive drift, as a tendency to rely on actual sensory experience, i.e., bottom-up processing, while lower proprioceptive drift served as an indicator of the prevalence of top-down, model-based influences. To reveal the bottom-up and top–down processes in cardioception, we performed a seed-based connectivity analysis of the heartbeat detection task, using as seeds the areas with known roles in sensory integration and entering proprioceptive drift as a covariate. The results revealed a left thalamus-dependent network positively associated with proprioceptive drift (bottom-up processing) and a left amygdala-dependent network negatively associated with drift (top-down processing). Bottom-up processing was related to thalamic connectivity with the left frontal operculum and anterior insula, anterior cingulate cortex, hypothalamus, right planum polare and right inferior frontal gyrus. Top-down processing was related to amygdalar connectivity with the rostral prefrontal cortex and an area involving the left frontal opercular and anterior insular cortex, with the latter area being an intersection of the two networks. Thus, we revealed the neural mechanisms underlying the integration of interoceptive information through the interaction between the current sensory experience and internal models.
Мозговые механизмы восприятия сопровождающих речь жестов при шизофрении: обзор
2021 · ARTICLE · ru
Поскольку нарушение процессов коммуникации является одним из ведущих проявлений шизофрении, для изучения природы этого заболевания необходимо лучшее понимание мозговой организации не только вербальной, но и невербальной коммуникации. Естественные жесты, сопровождающие устную речь, представляют собой один из важнейших каналов невербальной передачи информации. Обеднение жестикуляции часто встречается у пациентов с шизофренией, но лишь относительно недавно были получены данные о коррелирующих с этими проявлениями нейрофизиологических и нейроанатомических изменениях. По сравнению с активной жестикуляцией, восприятие жестов предоставляет значительно больше возможностей для нейрофизиологического исследования, так как не требует активного движения человека в процессе измерений или создания трудоемких экспертных аннотаций жестов каждого обследуемого. В то же время данных о мозговых механизмах восприятия жестов при шизофрении также крайне мало. В предлагаемом обзоре проанализированы уже существующие сведения и обсуждаются перспективные направления исследований мозговых механизмов восприятия спонтанных жестов при шизофрении. Чтобы прояснить контекст подобных исследований, кратко рассматриваются данные о мозговой организации сопровождающей речь жестикуляции и ее восприятия в норме, а также методы когнитивной и социальной нейронауки, с помощью которых такие данные могут быть получены.
Functional connectivity of the dorsolateral prefrontal cortex contributes to different components of executive functions
2020 · ARTICLE · en
Objective The dorsolateral prefrontal cortex (DLPFC) orchestrates other brain regions and plays a vital role for “the most uniquely human” executive functions (EFs), which are divided into distinct components. Components of EFs have been localized to different brain regions and at the same time the DLPFC was found to be involved in a majority of EF components. The possible mechanism of the DLPFC's contribution to EF components might be found in DLPFC functional connectivity (FC): this FC of the DLPFC with other brain regions contributes to different EF components. Method To explore the DLPFC FC contribution to different EFs, we used an integrative approach involving analysis of fMRI and neuropsychological assessment of EFs. Fifty healthy adults (27 females and 23 males, mean age 34.5 ± 16.6 years) underwent neuropsychological assessment of EFs as well as task-based and resting-state fMRI. Task-based fMRI was applied as a functional localizer for individually defined DLPFC ROIs that were further used for the FC seed-based correlation analysis of the resting-state data. Then we looked for associations between individual scores of different EF components and the whole-brain resting-state FC of the DLPFC. Results Resting-state correlates of DLPFC FC were revealed for three out of the seven EF components derived from an extensive neuropsychological assessment: inhibition, switching, and the verbal EF component. Conclusions Our study is the first to reveal the contribution of the DLPFC FC to several distinct EF components. The obtained results give insight into the brain mechanisms of EFs.
Modulation of intrinsic brain connectivity by implicit electroencephalographic neurofeedback
2020 · ARTICLE · en
Despite the increasing popularity of neurofeedback, its mechanisms of action are still poorly understood. This study aims to describe the processes underlying implicit electroencephalographic neurofeedback. Fifty-two healthy volunteers were randomly assigned to a single session of infra-low frequency neurofeedback or sham neurofeedback, with electrodes over the right middle temporal gyrus and the right inferior parietal lobule. They observed a moving rocket, the speed of which was modulated by the waveform derived from a band-limited infra-low frequency filter. Immediately before and after the session, the participants underwent a resting-state fMRI. Network-based statistical analysis was applied, comparing post- vs. pre-session and real vs. sham neurofeedback conditions. As a result, two phenomena were observed. First, we described a brain circuit related to the implicit neurofeedback process itself, consisting of the lateral occipital cortex, right dorsolateral prefrontal cortex, left orbitofrontal cortex, right ventral striatum, and bilateral dorsal striatum. Second, we found increased connectivity between key regions of the salience, language, and visual networks, which is indicative of integration in sensory processing. Thus, it appears that a single session of implicit infra-low frequency electroencephalographic neurofeedback leads to significant changes in intrinsic brain connectivity.
Context-dependency in the Cognitive Bias Task and Resting-state Functional Connectivity of the Dorsolateral Prefrontal Cortex
2020 · ARTICLE · en
Objective: Goldberg, the author of the “novelty-routinization” framework, suggested a new pair of cognitive styles for agent-centered decision-making (DM), context-dependency/independency (CD/CI), quantified by the Cognitive Bias Task (CBT) and supposedly reflecting functional brain hemispheric specialization. To date, there are only three lesion and activation neuroimaging studies on the CBT with the largest sample of 12 participants. The present study is the first to analyze whole-brain functional connectivity (FC) of the dorsolateral prefrontal cortex (DLPFC), involved in contextual agent-centered DM. Method: We compared whole-brain resting-state FC of the DLPFC between CD (n = 24) and CI (n = 22) healthy participants. Additionally, we investigated associations between CD/CI and different aspects of executive functions. Results: CD participants had stronger positive FC of the DLPFC with motor and visual regions; FC of the left DLPFC was more extensive. CI participants had stronger positive FC of the left DLPFC with right prefrontal and parietal-occipital areas and of the left and right DLPFC with ipsilateral cerebellar hemispheres. No sex differences were found. CD/CI had nonlinear associations with working memory. Conclusions: The findings suggest that CD and CI are associated with different patterns of DLPFC FC. While CD is associated with FC between DLPFC and areas presumably involved in storing representations of current situation, CI is more likely to be associated with FC between DLPFC and right-lateralized associative regions, probably involved in the inhibition of the CD response and switching from processing of incoming perceptual information to creation of original response strategies.
Мозговые механизмы нарушения модели психического при расстройствах аутистического спектра и шизофрении: обзор данных фМРТ
2020 · ARTICLE · ru
Модель психического – это сложная психическая функция, которая позволяет приписывать другим наличие внутреннего мира и конкретные психические явления (намерения, эмоции, мысли). Именно она позволяет людям полноценно интерпретировать поведение других и адаптироваться к нему. Ряд психических расстройств и расстройств развития психики связан с нарушениями модели психического, процесса коммуникации и общения с другими людьми. В связи с этим появилось множество исследований, посвященных мозговым механизмам модели психического и ее нарушений при патологии. Особый интерес среди них представляют работы, выполненные методом функциональной магнитно-резонансной томографии (фМРТ), поскольку данный метод позволяет неинвазивное изучение индивидуальных мозговых коррелятов высокоуровневых психических процессов (и в перспективе – диагностику их нарушений). Данный обзор посвящен фМРТ-методикам изучения различных компонентов модели психического (перцептивного, когнитивного, аффективного и имплицитного) и полученным с их помощью основным результатам. С опорой на континуальную модель нарушения модели психического Б. Креспи и К. Бэдкока, которая предполагает гипо- и гиперментализацию (недостаточное и чрезмерное приписывание психических явлений другим людям) при расстройствах аутистического и психотического спектров соответственно, анализируются мозговые механизмы нарушения различных компонентов модели психического по типу гипо- и гиперактивации их нейроанатомического субстрата при расстройствах аутистического спектра и шизофрении.
Macro- and microstructural changes in cosmonauts’ brains after long-duration spaceflight
2020 · ARTICLE · en
Long-duration spaceflight causes widespread physiological changes, although its effect on brain structure remains poorly understood. In this work, we acquired diffusion magnetic resonance imaging to investigate alterations of white matter (WM), gray matter (GM), and cerebrospinal fluid (CSF) compositions in each voxel, before, shortly after, and 7 months after long-duration spaceflight. We found increased WM in the cerebellum after spaceflight, providing the first clear evidence of sensorimotor neuroplasticity. At the region of interest level, this increase persisted 7 months after return to Earth. We also observe a widespread redistribution of CSF, with concomitant changes in the voxel fractions of adjacent GM. We show that these GM changes are the result of morphological changes rather than net tissue loss, which remained unclear from previous studies. Our study provides evidence of spaceflight-induced neuroplasticity to adapt motor strategies in space and evidence of fluid shift– induced mechanical changes in the brain.
Neural Correlates of Group Versus Individual Problem Solving Revealed by fMRI
2020 · ARTICLE · en
Group problem solving is a prototypical complex collective intellectual activity. Psychological research provides compelling evidence that problem solving in groups is both qualitatively and quantitatively different from doing so alone. However, the question of whether individual and collective problem solving involve the same neural substrate has not yet been addressed, mainly due to methodological limitations. In the current study, functional magnetic resonance imaging was performed to compare brain activation when participants solved Raven-like matrix problems in a small group and individually. In the group condition, the participant in the scanner was able to discuss the problem with other team members using a special communication device. In the individual condition, the participant was required to think aloud while solving the problem in the silent presence of the other team members. Greater activation was found in several brain regions during group problem solving, including the medial prefrontal cortex; lateral parietal, cingulate, precuneus and retrosplenial cortices; frontal and temporal poles. These areas have been identified as potential components of the so-called “social brain” on the basis of research using offline judgments of material related to socializing. Therefore, this study demonstrated the actual involvement of these regions in real-time social interactions, such as group problem solving. However, further connectivity analysis revealed that the social brain components are co-activated, but do not increase their coupling during cooperation as would be suggested for a holistic network. We suggest that the social mode of the brain may be described instead as a re-configuration of connectivity between basic networks, and we found decreased connectivity between the language and salience networks in the group compared to the individual condition. A control experiment showed that the findings from the main experiment cannot be entirely accounted for by discourse comprehension. Thus, the study demonstrates affordances provided by the presented new technique for neuroimaging the “group mind,” implementing the single-brain version of the secondperson neuroscience approach.
Using the RUPEX Multichannel Corpus in a Pilot fMRI Study on Speech Disfluencies
2020 · CHAPTER · en
In modern linguistics and psycholinguistics speech disfluencies in real fluent speech are a well-known phenomenon. But it’s not still clear which components of brain systems are involved into its comprehension in a listener’s brain. In this paper we provide a pilot neuroimaging study of the possible neural correlates of speech disfluencies perception, using a combination of the corpus and functional magnetic-resonance imaging (fMRI) methods. Special technical procedure of selecting stimulus material from Russian multichannel corpus RUPEX allowed to create fragments in terms of requirements for the fMRI BOLD temporal resolution. They contain isolated speech disfluencies and their clusters. Also, we used the referential task for participants fMRI scanning. As a result, it was demonstrated that annotated multichannel corpora like RUPEX can be an important resource for experimental research in interdisciplinary fields. Thus, different aspects of communication can be explored through the prism of brain activation.
Brain ventricular volume changes induced by long-duration spaceflight
2019 · ARTICLE · en
Long-duration spaceflight induces detrimental changes in human physiology. Its residual effects and mechanisms remain unclear. We prospectively investigated the changes in cerebrospinal fluid (CSF) volume of the brain ventricular regions in space crew by means of a region of interest analysis on structural brain scans. Cosmonaut MRI data were investigated preflight (n = 11), postflight (n = 11), and at long-term follow-up 7 mo after landing (n = 7). Post hoc analyses revealed a significant difference between preflight and postflight values for all supratentorial ventricular structures, i.e., lateral ventricle (mean % change ± SE = 13.3 ± 1.9), third ventricle (mean % change ± SE = 10.4 ± 1.1), and the total ventricular volume (mean % change ± SE = 11.6 ± 1.5) (all P
Курсы (1)
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Методы нейронауки · 5 раза
2025/2026, 2024/2025, 2023/2024, 2022/2023, 2021/2022 · Бакалавриат · рус