Феурра Маттео
Институт когнитивных нейронаук
Профессиональные интересы
Должности
- Доцент — Институт когнитивных нейронаук
Био
- · Начал работать в НИУ ВШЭ в 2014 году.
- · Научно-педагогический стаж: 11 лет.
Образование
- 2009 · PhD: Флорентийский университет, специальность 19.00.02 «Психофизиология», 19.00.00 «Психологические науки», 03.03.06 «Нейробиология»
- 2004 · Специалитет: Университет Флоренции, специальность «Психология», квалификация «Специалист»
- — · 2004 Laurea in Psicologia Sperimentale (пятигодичная комбинированная программа бакалавриат-магистратура по специальности Экспериментальная Психология), Флорентийский университет. 2009 PhD в Экспериментальной Психологии, Факультет Психологии, Флорентийский университет. Научные руководители: Prof. Nicoletta Berardi and Maria Pia Viggiano.
Опыт работы
- · 2014: с года НИУ ВШЭ
Гранты и проекты
- — · на соискание учёной степени кандидата наук
Конференции (5)
Показать все
- · 2016: Third annual conference Communication, Computation, and Cognitive Processes (СССР3) (Moscow). Доклад: The BDNF val66met polymorphism affects the level of processing effect of memory: A deep and shallow rTMS study
- · 2016: INTERNATIONAL CONFERENCE ON MEMORY (ICOM6) (Budapest). Доклад: Frequency-specific insight into short-term memory capacity
- · 2016: SOCIETY FOR NEUROSCIENCE (Chicago). Доклад: State-dependent impact of Transcranial Alternating Current Stimulation of the motor mirror system
- · 2015: 1st Moscow Conference with International Participation “TRANSCRANIAL MAGNETIC STIMULATION: FROM CURRENT STATE-OF-ART TO FUTURE HORIZONS” (Moscow). Доклад: STATE-DEPENDENT EFFECTS OF TRANSCRANIAL ALTERNATING CURRENT STIMULATION OF THE MOTOR SYSTEM
- · 2015: Summer Neurolinguistic School "Language and Brain Pathology". Доклад: Neuromodulation Treatment in Aphasia
Идентификаторы исследователя
- ORCID:
0000-0003-0934-6764 - ResearcherID:
K-1524-2019 - Google Scholar: https://scholar.google.com/citations?user=0xvTt84AAAAJ&hl=it
- Scopus AuthorID:
15047818300
Публикации (69)
Repetitive transcranial magnetic stimulation modulates action naming over the left but not right inferior frontal gyrus
2022 · ARTICLE · en
fMRI language mapping studies report right-hemispheric contribution to language in healthy individuals. However, it remains unclear whether these right-hemispheric patterns of activity are critical for language, which is highly relevant for clinical preoperative language mapping. The available findings are controversial. In this study, we first measured individual patterns of language lateralization with an fMRI language localizer in healthy participants with different handedness (N = 31). Then, the same participants received rTMS over the individual coordinates of peak fMRI-based activation in the left and right inferior frontal gyri. During rTMS, participants performed a picture naming task. It included both objects and actions to test whether naming of nouns and verbs would be equally modulated by rTMS. Stimulation of the left inferior frontal gyrus resulted in accuracy facilitation of verb production regardless of individual language lateralization. No modulation of object naming was found at any stimulation site in terms of accuracy nor reaction time. This study causally confirmed the critical contribution of the left, but not the right hemisphere to verb production regardless of the language lateralization patterns observed with fMRI. Also, the results stress that action rather than object naming is the task of choice for mapping language in the frontal lobe. © 2022, The Author(s), under exclusive licence to Springer-Verlag GmbH Germany, part of Springer Nature.
Chapter 16 - Noninvasive brain stimulation and brain oscillations
2022 · ARTICLE · en
Recent technological advances in the field of noninvasive brain stimulation (NIBS) have allowed to interact with endogenous brain oscillatory activity, the main neural communication code of our brain, opening new scenarios for transient modifications of cognitive and behavioral performances: such a possibility can be capitalized both for research purposes in subjects healthy, as well as in the context of therapeutic and rehabilitative settings. Among NiBS methodologies, transcranial magnetic stimulation (TMS) has been the first used to this purpose, and also thanks to the technical development of TMS-EEG co-registering systems, the mechanistic knowledge regarding the role of brain oscillations has been improved. Another approach to brain oscillations considers electric stimulation methods, such as transcranial direct current stimulation (tDCS), and especially transcranial alternating current stimulation (tACS), for which -however- some technical and conceptual caveats have emerged. In this chapter, we briefly review the uses of NiBS in this field up to now, by providing an update on the current status of research applications as well as of its attempts of exploitation in translational clinical applications, especially regarding motor disorders and for understanding and reducing some psychiatric symptoms.
Скорость обработки гиппокампом контекстуальной информации связана с ее конгруэнтностью ранее сформированным схемам
2022 · ARTICLE · ru
Одним из важнейших механизмов, обеспечивающих гибкую регуляцию поведения, является способность сличать и интегрировать имеющуюся у субъекта информацию о мире с информацией, постоянно поступающей извне. В настоящей работе мы с помощью стереоэлектроэнцефалографии регистрировали гиппокампальный локальный полевой потенциал у испытуемых, выполнявших задачу на оценку конгруэнтности пар стимулов “предмет–контекст”. Мы показали, что гиппокамп вовлечен в обработку информации о конгруэнтности предмета контексту. Обработка информации, конгруэнтной cформированному ранее семантическому знанию, сопровождается более ранней активацией гиппокампа по сравнению с обработкой информации, требующей установления новых ассоциативных связей.
Single gene polymorphisms as a predictor of noninvasive brain stimulation effectiveness (commentary on Pellegrini et al, 2021)
2022 · ARTICLE · en
The field of noninvasive brain stimulation (NIBS) including transcranial direct current stimulation (tDCS), transcranial alternating current stimulation (tACS) and transcranial magnetic stimulation (TMS) has been growing exponentially since the last decade of the 20th century (Krishnan et al., 2015; Meeker et al., 2020). This is because NIBS has enabled us to move from the correlational studies performed using electroencephalography (EEG), magnetoencephalography (MEG), functional magnetic resonance imaging (fMRI) or near-infrared spectroscopy (NIRS) to causational studies, where we can directly observe the effects of stimulation on a specific part of the brain (especially in the case of TMS; Farzan et al., 2016).
Impact of β-range-induced oscillatory activity on human input–output relationship of the corticospinal pathway
2021 · ARTICLE · en
Objective : The aim of the study was to show that short-lasting (90 s) transcranial alternating current stimulation (tACS) at 20 Hz delivered over the left primary motor cortex (M1) is able to change the shape of recruitment curve of the corticospinal pathway. Methods : The corticospinal pathway was studied during tACS by means of the relationship between the intensity of transcranial magnetic stimulation (TMS) delivered over the left M1 and corresponding motor evoked potentials (MEPs) recorded from the right first dorsal interosseus muscle (FDI), in nine healthy subjects. In order to extract characteristics of the input – output relationship that have particular physiological relevance, data were fitted to the Boltzmann sigmoidal function by the Levenberg – Marquardt nonlinear, least mean squares algorithm. Results : The β-rhythm tACS influenced the shape and parameters of the input – output relation, so that the initial segment of the conditioned curve (from threshold to 30% of maximum muscle size) diverged, while the subsequent segment converged to overlap the unconditioned control curve. Discussion : β-rhythm tACS conditions only a definite subset of corticospinal elements influencing less than 30% of the entire motoneuronal pool. The fact that β-rhythm tACS mainly affects the most excitable motoneurons could explain the observed antikinetic effect of the tACS at β-rhythm applied in the motor regions.
Online and offline effects of transcranial alternating current stimulation of the primary motor cortex
2021 · ARTICLE · en
Transcranial alternating current stimulation (tACS) is a non-invasive brain stimulation technique that allows interaction with endogenous cortical oscillatory rhythms by means of external sinusoidal potentials. The physiological mechanisms underlying tACS effects are still under debate. Whereas online (e.g., ongoing) tACS over the motor cortex induces robust state-, phase- and frequency-dependent effects on cortical excitability, the offline effects (i.e. after-effects) of tACS are less clear. Here, we explored online and offline effects of tACS in two single-blind, sham-controlled experiments. In both experiments we used neuronavigated transcranial magnetic stimulation (TMS) of the primary motor cortex (M1) as a probe to index changes of cortical excitability and delivered M1 tACS at 10 Hz (alpha), 20 Hz (beta) and sham (30 s of low-frequency transcranial random noise stimulation; tRNS). Corticospinal excitability was measured by single pulse TMS-induced motor evoked potentials (MEPs). tACS was delivered online in Experiment 1 and offline in Experiment 2. In Experiment 1, the increase of MEPs size was maximal with the 20 Hz stimulation, however in Experiment 2 neither the 10 Hz nor the 20 Hz stimulation induced tACS offline effects. These findings support the idea that tACS affects cortical excitability only during online application, at least when delivered on the scalp overlying M1, thereby contributing to the development of effective protocols that can be applied to clinical populations.
The immersive 3D objects’ library for applying non-invasive brain stimulation in research on the motor control and the mirror neurons system: a call for collaboration
2021 · ARTICLE · en
We have developed and tested a library of 3D objects for the study of motor control in immersive reality (https://p3d.in/TK7k3). The use of this stimulus material (e.g., as on the Figure 4a) opens up new opportunities for evaluating physiological parameters when using the method of neurotherapy in virtual reality. In combination with the Non-Invasive Brain Stimulation (NIBS) methods such as Transcranial Magnetic Stimulation (TMS), we propose to explore the effects of functional activity of the mirror neuron system on a large scale for further approbation of advanced and promising neurorehabilitation protocols.
Examining the effects of transcranial direct current stimulation on human episodic memory with machine learning
2020 · ARTICLE · en
We aimed to replicate a published effect of transcranial direct-current stimulation (tDCS) -induced recognition enhancement over the human ventrolateral prefrontal cortex [1] and analyze the data with machine learning. We investigated effects over an adjacent region, the dorsolateral PFC. We found weak or absent effects over the VLPFC and DLPFC. We conducted machine learning studies to examine the effects of semantic and phonetic features on memorization, which revealed no effect of VLPFC tDCS on the original dataset or the current data. The highest contributing factor to memory performance was individual differences in memory not explained by word features, tDCS group, or sample size, while semantic, phonetic, and orthographic word characteristics did not contribute significantly. To our knowledge,We aimed to replicate a published effect of transcranial direct-current stimulation (tDCS) - induced recognition enhancement over the human ventrolateral prefrontal cortex (VLPFC) and analyze the data with machine learning. We investigated effects over an adjacent region, the dorsolateral prefrontal cortex (DLPFC). In total, we analyzed data from 97 participants after exclusions. We found weak or absent effects over the VLPFC and DLPFC. We conducted machine learning studies to examine the effects of semantic and phonetic features on memorization, which revealed no effect of VLPFC tDCS on the original dataset or the current data. The highest contributing factor to memory performance was individual differencesin memory not explained by word features, tDCS group, or sample size, while semantic, phonetic, and orthographic word characteristics did not contribute significantly. To our knowledge, this is the first tDCS study to investigate cognitive effects with machine learning, and future studies may benefit from studying physiological as well as cognitive effects with data-driven approaches and computational models.
Transcranial alternating current stimulation of the primary motor cortex: intensity effects
2019 · ARTICLE · en
Transcranial alternating current stimulation (tACS) can be used to modulate brain activity. tACS was shown to induce frequency-, state-, and phase- dependent effects which makes tACS a neurostimulation technique that provides a more valuable predictable outcome. However, the impact of different tACS intensities has not been systematically investigated yet. Here, we proposed to investigate the effects of tACS of the primary motor cortex (M1) delivered at different intensities. There is a common assumption that application of stimulation for longer duration or for higher intensity leads to more reliable physiological and behavioral effects. However, previous studies performed using different transcranial electrical stimulation methods such as transcranial direct current stimulation (tDCS) and/or at high-frequency such as tACS at ripple range, showed non-monotonic effect of stimulation intensity. Nevertheless, tDCS and high-frequency tACS potentially rely on different mechanisms of neuromodulation with respect to conventional tACS delivered at EEG range (1 – 70 Hz). In this study we applied 20 Hz tACS to the primary motor cortex (M1) to investigate potential non-monotonic effect of tACS intensities (ranging from 0.25 mA to 2 mA with 0.25 mA interval between conditions) on the M1 excitability measured as the peak-to-peak amplitude of TMS-induced motor evoked potentials (MEPs). As for control, we used 1 mA 10 Hz (alpha) tACS and a no stimulation condition. Preliminary results (N = 9) showed increase of MEPs for higher intensities (1.5 mA, 2 mA) of stimulation. In addition, an interesting effect emerged for those subjects with a lower motor threshold which showed a higher MEPs modulation effect of beta-tACS
Transcranial direct current stimulation effects on memory consolidation: timing matters.
2019 · ARTICLE · en
Transcranial direct current stimulation (tDCS) is a promising tool for modulation of learning and memory, allowing to transiently change cortical excitability of specific brain regions with physiological and behavioral outcomes. A detailed exploration of factors that can moderate tDCS effects on episodic long-term memory (LTM) is of high interest due to the clinical potential for patients with traumatic or pathological memory deficits and with cognitive impairments. This commentary discusses findings by Marián et al. (2018) recently published in Cortex within a broad context of brain stimulation in memory research.
Курсы (3)
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Cognitive Neuroscience · 5 раза
2025/2026, 2024/2025, 2023/2024, 2022/2023, 2021/2022 · Курс обязательный / Магистратура / Маго-лего · Анг
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Multimodal Neuroimaging Part 2 · 3 раза
2025/2026, 2024/2025, 2023/2024 · Магистратура / Маго-лего · Анг
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Advanced Neuroimaging · 2 раза
2022/2023, 2021/2022 · Магистратура / Маго-лего · Анг